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Shantha extends its excellent in house expertise, core competencies and skill in development of vaccines and biologicals to carry out contract research services to its clients. Our clients are assured of high quality, cost-effective and timely services with strict adherence to the provisions of confidentiality and intellectual property rights.

 
     
  The scope of services on offer extends over a wide spectrum of biotechnology research and includes the following:  
 
   
  Molecular cloning and expression of native and synthetic genes in various systems like bacteria, yeast and mammalian cells.
  Development and characterization of cell lines for products of diagnostic or therapeutic use
  Fermentation and purification process development and production of pre-clinical grade material as per cGMP
  Polyclonal and monoclonal antibody development against any desired antigen
  Production and purification of monoclonal antibodies from ascitic fluid or from cultured mammalian cells
  Chimerization/humanization of mouse antibodies for therapeutic applications
  Development of human monoclonal antibodies for therapeutic applications
  ScFv Development
 
     
 

Contract research is undertaken at Shantha’s sprawling 50,000 sq. ft. R&D center, which includes an 8000 sq. ft. of class 10,000 area. The center is well-equipped with the latest world class instruments and other support facilities.

 
 
Shantha has already carried out substantial work for its clients. The contract research work undertaken is in the areas of:
 
 
   
  Gene cloning
  Monoclonal antibody development
  Expression and purification of recombinant proteins by fermentation
  Fermentation/Purification Process optimization
  Development of polyclonal antibodies
  Development of WCB and MCB
  Analytical method